The generality of kinase-catalyzed biotinylation
نویسندگان
چکیده
منابع مشابه
A minimal peptide substrate in biotin holoenzyme synthetase-catalyzed biotinylation.
The Escherichia coli biotin holoenzyme synthetase, BirA, catalyzes transfer of biotin to the epsilon amino group of a specific lysine residue of the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase. Sequences of naturally biotinylated substrates are highly conserved across evolutionary boundaries, and cross-species biotinylation has been demonstrated in several systems. ...
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ژورنال
عنوان ژورنال: Bioorganic & Medicinal Chemistry
سال: 2016
ISSN: 0968-0896
DOI: 10.1016/j.bmc.2015.11.029